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While we are disappointed to discontinue the development of danuglipron, we remain committed to evaluating and advancing promising programs in an effort to bring innovative new medicines to patients, said Chris Boshoff, Pfizers chief scientific officer and head of R&D, in a statement
Until then, any use outside of a clinical trial setting would be considered off-label and is not currently recommended
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Molecular Properties Property Value Systematic Name Aib-His-D-2-Nal-D-Phe-Lys-NH Molecular Formula CHNO Molecular Weight 711.85 Da CAS Number 170851-70-4 Structure Class Synthetic pentapeptide Receptor Target GHS-R1a (growth hormone secretagogue receptor type 1a) Development Novo Nordisk (NNC 26-0161) The sequence includes -aminoisobutyric acid (Aib) at position 1, D-2-naphthylalanine (D-2-Nal) at position 3, and D-phenylalanine (D-Phe) at position 4