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Additional studies have found that loss of forkhead box protein P1 ( Foxp)1 and forkhead box protein P4 (Foxp4) in mice can induce ectopic expression of NPY in airway epithelia, resulting in airway hyperresponsiveness [172]

This is important because weight loss itself can reduce inflammation

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A mendelian randomization study has found that hyperthyroidism can cause hemodynamic changes, which results in cardiovascular diseases represented by atrial fibrillation (AF) (113, 114)