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Likewise, the pharmacological option has been investigated with the negative regulation of NRF-2, mainly with cytotoxic agents, as in acute monocytic leukemia [105]

These are believed to be related to VEGF inhibition in the bloodstream , though the risk remains low in Eylea treatment

Increasing evidence suggests that alternative molecular mechanismssuch as tau pathology, neuroinflammation, mitochondrial dysfunction, brain insulin resistance, and vascular impairmentplay critical roles in disease progression

The medication makes the process more achievable, but the strategy makes it successful