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Its about controlling everything else sugar, fatty liver, lipids.
Type 2 Diabetes (Oral Therapy) Orforglipron ACHIEVE-3 directly demonstrated orforglipron 36 mg superiority over oral semaglutide 14 mg for HbA1c reduction (2.2% vs 1.4%) and weight loss (9.2% vs 5.3%) in type 2 diabetes
You cant really compare the two since they have different purposes
Based on magnetic resonance spectroscopy, livers of obese subjects were classified with no steatosis ( 15%, n = 40), revealing that the presence of NAFLD, but not the amount of hepatic triglycerides, was associated with hepatic insulin resistance [72]
When blood sugar drops, the body releases adrenaline and cortisol
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