It is mainly found in the brush borders of epithelial cells of the proximal convoluted tubules in the kidney, in the small and large intestine, prostate tissue, hepatocytes, fibroblasts and in activated leukocytes [3033], preferentially cleaving peptide hormones containing a position two alanine or proline [27]
Measuring C-peptide levels provides an indirect measure of how much residual beta cells a T1DM patient has (Insulin degrades quickly and T1DM require exogenous insulin to survive, meaning that insulin measurements are not reliable for the purpose of measuring residual beta cells)
And then the last one was proprietary initiatives
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Retatrutide is a more recently developed investigational compound a triple agonist targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously
