Since the blood-brain barrier prevents many dietary antioxidants from entering the brain, it largely relies on endogenous antioxidants such as Cu- and Zn-dependent superoxide dismutase (Cu, Zn SOD1)
DOI: 10.2147/JIR.S391859 [Google Scholar] Noyan-Ashraf MH, Momen MA, Ban K, Sadi AM, Zhou YQ, Riazi AM, et al
Two recent clinical studies also reported remarkably upregulated PPAR expression in red blood cells, boosted serum GSH and GPX levels and decreased serum MAD contents after treatment with curcumin (500 mg/day, P.O for 8 weeks
It sits among many options
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