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Methods SURMOUNT-2 participants were randomly assigned (1:1:1) to receive either tirzepatide 10 mg ( n = 312), tirzepatide 15 mg ( n = 311), or placebo ( n = 315) for 72 weeks as an adjunct to diet and exercise

Lack of clinical trial data: Mounjaro's clinical development programme did not specifically study cannabis users, so interaction data are not available from controlled studies

Ozempic users spark spike in ER visits: Shocking new side effects

Also, in the experiments on human breast cancer cells, Won and Seo found that the inactivation of PI3K/Akt/mTORC1 signaling pathway promotes the expression of caspases and Bax leading to increased apoptosis [302]

NEJM, 2025 6