Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells
in Encyclopedia of Gastroenterology (ed
Data were collected from research articles published up to March 2025, sourced from eight well - known databases: PubMed, Web of Science, ScienceDirect, Google Scholar, SciFinder, ResearchGate, Scopus, and the China National Knowledge Infrastructure (CNKI)
Hepatic effects that are considered adverse include death, abnormal clinical chemistry parameters, obvious functional organ impairment, DNA and mitochondrial alteration, glutathione depletion, hepatocyte necrosis, enhanced replicative DNA synthesis, generation of reactive oxygen species, and increased peroxisome proliferation (in rodents) (Williams and Iatropoulos 2002)
Upon comparing the different treatment across the genotype, we observed that WT mice exhibit no expression changes upon cagrilintide or sCT treatment in the DVC and LPBN (Fig