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It has been granted GRAS (Generally Recognized as Safe) status by the FDA for use as a food supplement ingredient, though this is distinct from drug approval

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[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Badulescu S., Tabassum A., Le G.H., Wong S., Phan L., Gill H., Llach C.D., McIntyre R.S., Rosenblat J., Mansur R

2 mg Weeks 14 Introductory dose to establish tolerability