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Downregulated GPX4 expression increases the susceptibility of cells to ferroptosis, whereas upregulated GPX4 expression has the opposite impact [24]

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Key Factors in Hair Loss Diminished Blood Supply: Reduced scalp blood flow can starve follicles of nutrients, weakening hair and causing loss

ROS production was then assessed by using the ROS-Glo HO Assay kit (Promega, Madison, MI, United States), following the manufacturers protocol

SASP are phenotypic changes such as the formation of bioactive secretome, triggered by a stress responsecellular senescence