Theyre taken by mouth to support or improve some aspect of health
Pituitary primordia were explanted from 11-day-old rat fetuses and cultured in a synthetic medium enriched with either DSIP at several concentrations, GnRH (10(-9) M) or TRH (10(-9) M)
Certain Bifidobacterium and Lactobacillus species can produce GABA 296,297,298,299,300 , and oral treatment with GABA or bacteria that produce GABA improves metabolic parameters in mice 298,301
Medically reviewed by Missy Zammichieli, DNP, APRN, FNP-BC Updated March 26, 2026 HEAD-TO-HEAD HOW THEY WORK (AND WHY IT MATTERS) Both medications mimic gut hormones that your body produces naturally after eating
The best outcomes usually come from combining medical tools with nutrition, strength training, sleep support, metabolic monitoring, and ongoing clinical judgment