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Materials and methods Ethic statements The animal studies were carried out in strict accordance with the Detailed Rules for the Administration of Animal Experiments for Medical Research Purposes issued by the Ministry of Health of the Peoples Republic of China and were approved by the Animal Experiment Administration Committee of The Fourth Military Medical University

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BMJ Open 13 , e072110 (2023)

Malabsorption (insufficient absorption of vitamin B 12 in the intestine), insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and required to absorb vitamin B 12 ), Diseases in the end section of the ileum (part of the small intestine), e.g

Ongoing research continues to uncover effects across multiple organ systems