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This was a randomized, head-to-head comparison that enrolled 751 individuals and found those who took tirzepatide lost 20% of their body weight, about 50 pounds on average, while those on semaglutide lost 14% of their body weight, or about 33 pounds on average

Because of these effects, GLP-1 is a big focus in type 2 diabetes treatment and weight management research

Regarding contraception, for most GLP-1 medications (semaglutide, liraglutide), there is no clinically significant effect on oral contraceptive effectiveness

doi: 10.1186/s13063-021-05442-y 161 ChenHLiuSGaoSShiHYanYXuYet al

You may be eligible to file an AFFF Lawsuit if you or a loved one was exposed to firefighting foam and subsequently developed cancer