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GLP-1 drugs are a class of medications used to treat diabetes and obesity by regulating appetite and blood sugar

For example, in June 2025, California updated its compounding regulations to require pharmacists to verify and document that compounded products produce a clinically significant difference, although pharmacists are not required to make independent clinical determinations

Both semaglutide and tirzepatide have been on the shortage list at various points, which has allowed compounding pharmacies to produce these medications legally

Furuhashi M, Fuseya T, Murata M, Hoshina K, Ishimura S, Mita T, et al

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