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Once secreted into the bloodstream, GLP-1 travels to target tissues including the pancreas, brain, and stomach

This mechanism may be particularly relevant for patients who had significant insulin resistance before starting GLP-1 therapy

Five to six eating occasions of 200-300 calories each prevent the stomach distension that triggers nausea while maintaining adequate nutrition

It is not available on the NHS, holds no UK Summary of Product Characteristics, and any retatrutide outside formal clinical trials is classified as a research chemical

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