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251 However, aurora kinase A (AURKA), an important mitosis regulator, increases the phosphorylation of GSK-3 and inactivates the protein destruction complex, which stimulates the upregulation of -catenin expression and promotes liver regeneration

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25 Finasteride Mechanism of action

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We found no evidence of downregulation in the overall cellular capacity to generate cAMP, as responses to the direct adenylate cyclase activator forskolin were unchanged after prolonged agonist stimulation (Fig