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Anecdotal reports from Phase 2 participants suggest that nausea severity is higher when dosing occurs in the early morning on an empty stomach, possibly because fasting amplifies the compound's gastric-slowing effect

These comprehensive benefits make retatrutide a promising option for individuals struggling with obesity and related metabolic disorders

These genetic markers may help provide context for why certain individuals experience more pronounced diarrhea during therapy

Less common but more serious concerns include gallbladder disease, pancreatitis and kidney injury associated with dehydration

Himss stock fell more than 27% following the announcement