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For example, combinations of GLP-1/glucagon RA achieve more liver fat content reduction in people with MASLD compared to GLP-1 RA alone despite similar WL, likely due to the direct effect of glucagon on hepatic lipid oxidation [79]

These products use the same delivery method and dosages

In the STEP 4 trial, participants who had already tolerated a 20-week run-in found continued treatment at the maintenance dose well tolerated

These injections are not FDA-approved for weight loss and can cause side effects such as infection, scarring, and uneven skin texture

Historically, GLP-1 receptor agonists were firmly embedded within endocrinology