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1 Introduction Prostate cancer (PCa) ranks as the second most common cancer in men and is the sixth leading cause of cancer-related deaths among them (Wala et al., 2023), the development of castration resistance is an inevitable outcome

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On the other hand, spontaneous and often substantial functional improvements [53,54,55] after partial lesioning of the spinal cord are associated with the spontaneous sprouting of axons in the corticospinal tract [56,57,58] and the formation of neural circuits by spared spinal cord tissue [26]

There are two questionable selenium deficiency diseases, Kashin-Beck disease and Keshan disease

Therefore, it is essential to monitor kidney health and consult healthcare professionals when considering these supplements