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2022 Profit: Otsuka Holdings had a profit of 137.42 billion JPY ($1.05 billion USD) in 2022, a 5.97 percent increase from 129.21 billion JPY ($1.18 billion USD) in 2021

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On abdominal physical exam, there was diffuse abdominal tenderness without guarding or rebound

[8] Otvos Jr, L., & Wade, J

In ovalbumin-induced mouse asthma models, L-theanine treatment could reduce the transport of inflammatory cells to bronchoalveolar lavage fluid (BALF) and inhibit the infiltration of inflammatory cells via blocking the activation of NF-B pathway and its downstream production of ROS, monocyte chemoattractant protein-1 (MCP-1), IL-4, IL-5, IL-13, TNF-, and interferon (IFN)- in BALF (35)