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This can be achieved by crossing the blood-brain-barrier involving saturable mechanisms (Banks et al., 2002), by diffusing through fenestrated capillaries at circumventricular organs (Uriarte et al., 2021), or by crossing the blood-cerebrospinal barrier (Uriarte et al., 2019)

However, in certain childrenparticularly those with genetic differences in glutathione metabolism or already under oxidative stressTylenol may interact with these vulnerabilities and play a role

doi: 10.1142/S0192415X25500326 133 XuHWangLYanKZhuHPanHYangHet al

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