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Some biomarkers (oxidative stress, antioxidant capacity) may shift within 24 weeks, while functional improvements may take 812 weeks or longer depending on dose, route, and baseline status

5 Journal of Endocrinology (PubMed)GHRP-6 induces growth-hormone release in preclinical models via the GHS receptor

Still, Pfizer has other experimental obesity drugs in its pipeline in the early stages of development that appear to work differently from its now-discontinued treatments

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Ipamorelin is a growth hormone secretagogue that stimulates the pituitary gland to release endogenous growth hormone, while CJC-1295 no DAC improves the durability and effectiveness of this response