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On the one hand are microflora-associated metabolites such as short-chain fatty acids, tryptophan metabolites, immunostimulants and endogenous cannabinoids that may play a mediating role

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& Herreros, J

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246 SIRT3, on the other hand, inhibits apoptosis and promotes cell growth, increases glycolytic metabolism, 247 maintains mitochondrial membrane integrity, 248 promotes mitochondrial DNA repair 249,250,251 and increases cell resistance to environmental stress

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