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There are several reasons a person may lack either of these substances, but when this is the cause of a deficiency they may require B12 injections or supplements, under the supervision of a health practitioner

Capsule format is used in oral-research and analytical contexts where dry, pre-measured administration is preferred over a reconstituted solution

No long-term safety data exists for any of these compounds in humans

However, combined supplementation with B12, B6, and folic acid may increase the risk of cataract extraction (37)

Vitamin B12 is quantitatively and rapidly absorbed from intramuscular and subcutaneous sites of injection