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(92) reported that while both variants were significantly less stable compared to WT, G6PD Plymouth was more severely affected than G6PD Mahidol

Primary Handling Editor: Ming Yang, in collaboration with the Nature Medicine team

Dietary changes Eat smaller, more frequent meals instead of large ones

Proteomic analyses have identified altered exosomal protein profiles in patients with HT showing notable upregulation of proteins like hepatocyte growth factor-like protein (HGFL), focal adhesion kinase 1 (FAK1), and tyrosine-protein phosphatase non-receptor type 12 (PTPN12), and downregulation of proteins including proteasome inhibitor PI31 subunit (PSMF1) and cystatin-M (CYTM) playing key roles in regulating processes related to inflammation, immune response and proliferation [28]