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Peptides are strings of amino acids, smaller than a protein

In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection

(PubMed) Alehagen U, Aaseth J, Alexander J, Johansson P

Plant Physiol 109:10471057 Gollan PJ, Trotta A, Bajwa AA, Mancini I, Aro E-M (2021) Characterization of the free and membrane-associated fractions of the thylakoid lumen proteome in Arabidopsis thaliana

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