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Moreover, DDX3X nuclear recruitment was dependent on the entire NEC machinery including the soluble pU L 31 protein, but also the pU L 34 transmembrane protein, which is essential to anchor pU L 31 to the nuclear envelope, as well as the pU S 3 viral kinase that impacts the nuclear localisation of the NEC

This modification would also provide CMS with additional time to monitor implementation progress, including data collection burden and response rates

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