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Participants often experience a decrease in BMI and improved metabolic profiles

Combined Therapies: Selenium supplementation is often part of a broader treatment plan that includes dietary changes (e.g., the Autoimmune Protocol), stress management, and conventional medical treatments

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A 2026 analysis in the Journal of Medical Internet Research found real-world discontinuation rates far exceed clinical trial numbers, with up to 70% of patients stopping treatment within 24 months -- often because of these effects