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When identified, treatment with high-dose folinic acid (leucovorin calcium) may bypass this blockage and restore brain folate levels

A great gentle serum is the La Roche Posay Glycolic Acid Serum with Kojic Acid and Vitamin B5 and PCA SKIN Hydroquinone-Free Pigment Gel is also a great option

[DOI] [PubMed] [Google Scholar] [27].Singh RP, La Cava A, Hahn BH

This culminates in immune destruction of the epithelium in exocrine glands, which causes the most common manifestations of the disease