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In addition to proliferation of peroxisomes, in cynomologus monkeys, fibrate-induced liver changes are associated with an increase in the number of mitochondria, which parallels the magnitude of the increase in peroxisomes (Cariello et al

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Brugger J, Schick MA, Brock RW, Baumann A, Muellenbach RM, Roewer N, Wunder C: Carbon monoxide has antioxidative properties in the liver involving p38 MAP kinase pathway in a murine model of systemic inflammation