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2,3 In a Phase I multiple-dose clinical trial conducted in healthy adults, pharmacokinetics were dose-proportional, accompanied by reductions in both fasting and oral glucose tolerance glucose levels

Some researchers attempt to salvage marginally exposed vials by immediately returning them to 28C and using them within 7 days rather than the standard 28-day window, but this creates uncertainty in downstream data

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A history of gallstones, gallbladder disease, pancreatitis, rapid weight loss, or a family history of gallstones should be discussed with the prescribing clinician

61(3): 3116 Korecka JA, Verhaagen J, Hol EM