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Mitochondria are essential organelles, whose dysfunction is central to major diseases 13,14 , as they are the center for aerobic ATP generation from oxidative phosphorylation (Oxphos) in the electron transport chain (ETC)

Transamination can thus be linked to deamination, effectively allowing nitrogen from the amine groups of amino acids to be removed, via glutamate as an intermediate, and finally excreted from the body in the form of urea