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2 In comparison with other B vitamins, B 12 is not synthesized by animals, fungi, or plants

Response: Regarding commenters' requests for exclusion criteria, we note that the measure methodology, including consideration of potential exclusions, was informed by extensive literature review, empiric analyses, and feedback from the TEP, PFE Work Group, and the public comment period held during measure development

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However, most standard protocols using subcutaneous administration follow the lower dosing ranges outlined above

Those numbers buy you a licensed medical provider, a 503A compounding pharmacy supply chain, individualized dosing, in-person injection training, and follow-up at the clinic