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Kidneys and plasma were collected 1 month after the end of DOX treatment from mice maintained under a standard 12 hour light/12 hour dark cycle with ad libitum feeding (sampled every 4 hours over a 24 hour cycle

Andreeff M , Kreis W, Miller W, Gee T, Berman E, Kolitz J, Kempin S, Straus D, Reich A, Tafuri A, Espiritu E, Deere M, Clarkson B

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Alongside impairments in carbohydrate metabolism, evidence of reduced carnitine levels suggest a dysfunction in mitochondrial -oxidation, leading to accumulation of long-chain fatty acids and elevated markers of lipid elongation and desaturation (Filipek et al., 2004

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