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Pathway analysis revealed significant disruptions in purine metabolism, amino acid metabolism, and protein synthesis, with notable sex-specific differences

"If we just look in the last couple of years, beyond lowering blood sugar and beyond reducing body weight, we have seen that these medicines reduce the rates of heart attacks and strokes and reduce the rates of diabetic kidney disease and are helpful for people with obstructive sleep apnea and reduce disability in people with arthritis and prevent the development of severe metabolic liver disease

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