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GHK-Cu and copper uglies Albeit rare, some people may experience a side effect from using GHK-Cu or other copper peptides known as copper uglies. Though there arent any studies on this phenomenon, some users have anecdotal reports of copper peptide skin care products leading to what looks like accelerated skin aging instead of antiaging

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2021 Apr;13(2):259

Emerging role of substance and energy metabolism associated with neuroendocrine regulation in tumor cells