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Seek immediate medical attention for: Severe, persistent abdominal pain, especially if different from typical IBS pain or radiating to the back (possible pancreatitis) Persistent vomiting preventing adequate fluid intake Signs of dehydration (decreased urination, dizziness, extreme thirst) Severe constipation lasting more than 3-4 days without bowel movement Blood in stool or black, tarry stools Yellowing of skin/eyes, right upper quadrant pain (possible gallbladder disease) Markedly reduced urination (possible acute kidney injury) Fever accompanying gastrointestinal symptoms Neck mass, difficulty swallowing, persistent hoarseness (thyroid concerns) Allergic reactions (rash, itching, swelling, severe dizziness) Scheduled follow-up should occur within 4-6 weeks of initiating therapy and after each dose escalation

"We shouldn't be able to make a judgment call on how a person has chosen to address this disease, whether they've chosen lifestyle or behavioral modifications, whether they've chosen medicines or whether they've chosen metabolic or bariatric surgery or, for many of my patients, all of the above," Stanford told ABC News

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17 BPC-157 has demonstrated efficacy in promoting corneal healing and maintaining transparency

However, GIP also influences lipid metabolism and energy storage, particularly in adipose tissue, where it can promote fat storage under certain conditions