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10.1002/ptr.5957 5 BaillargeonJ.LangevinA

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When incorporated into scaffold matrices and hydrogel formulations, thymosin beta-4 has been shown to support endothelial and epicardial cell proliferation, enhance blood vessel formation, and promote myocardial tissue repair in post-ischemic models

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These interventions aim to deliver targeted symptom relief directly within the joint space, with the principal agents including corticosteroids, hyaluronic acid (HA), and emerging biologics such as platelet-rich plasma (PRP) and cell-based products (Wehling et al., 2017