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A comparison of our Sas Pcob structure with other photocobilin proteins (predicted structures obtained from the recently published Alphafold2 database 26 ), shows they can be divided into three main groups depending on the location of the AdoCbl-binding domain at either the N- or C-terminus, and whether they contain the additional output domain in the fused proteins (Supplementary Figs

Researchers may consider investigating either separately or combining both to study how they interact in settings like injury recovery

Some are designed to influence appetite

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Stress: Manage stress with evidence-based practices, since it influences overall healing