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10.1006/abio.1997.2391 [DOI] [PubMed] [Google Scholar] Zhou W, Hu G, He J et al (2022) SENP1-Sirt3 signaling promotes -ketoglutarate production during M2 macrophage polarization

Excess ROS then activates the NLRP3 inflammasome in microglia, promoting maturation and release of IL-1 (Xiao et al., 2021)

These findings lend support to the hypothesis that high levels of oxidative stress may contribute to the pathophysiology of depressionthough its effects may be anatomically selective

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1.El glutatin es un antioxidante muy fuerte, en parte porque se pueden encontrar altas concentraciones en todas las clulas del cuerpo