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In vivo and in vitro investigations of schisandrin B against angiotensin II induced ferroptosis and atrial fibrosis by regulation of the SIRT1 pathway
Over time, heavy drinking can lead to liver damage, including cirrhosis
Regular monitoring is recommended
Learning objectives Describe Ehlers Danlos syndrome Recognize the symptoms and signs of Ehlers Danlos syndrome Anesthetic management of a patient with Ehlers Danlos syndrome Definition and mechanisms Ehlers Danlos syndrome (EDS) comprises a group of clinically and genetically heterogeneous heritable connective tissue disorders, characterized by joint hypermobility and instability, skin texture anomalies, and vascular and internal organ fragility Clinical manifestations range from extremely mild phenotypes to life-threatening complications depending on the specific subtype The current Villefranche nosology recognizes six major subtypes, comprising classic, hypermobile, vascular, kyphoscoliotic, arthrochalasia, and dermatosparaxis, most of which are linked to mutations in one of the genes encoding for fibrillar collagen proteins or enzymes involved in post-translational modification of these proteins AD, autosomal dominant
Moher, D., SPIRIT 2013 statement: defining standard protocol items for clinical trials
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