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It also improves energy metabolism and vitality of the animals
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Figure 8: Changes in gastrocnemius muscle atrophy between left and right hind limbs, across the 10 experimental treatment groups
ROS-induced apoptosis also explains the beneficial effect of two analogs of nuclear receptor ligands in several types of cancer: 2-methoxyestradiol, a 17-estradiol metabolite, and N-(4-hydroxyphenyl) retinamide, a synthetic analog of retinoic acid, have been shown to induce PCD in neuroblastoma and lung cancer cells, respectively 104,105