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2024;47 doi: 10.1016/j.lanepe.2024.101098

As a result, lifestyle interventions alone, such as diet and exercise, are often insufficient, and effective management typically requires a combination of strategies to address the underlying biology of obesity. The group explored data from more than 60,000 patients who originally participated in one of 56 randomized controlled trials (RCTs)

These medications enhance the bodys natural responses to eating, leading to improved satiety and reduced hunger, which can help decrease overall caloric intake

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The sustained receptor activation that makes pharmaceutical GLP-1 medications so effective simply cannot be replicated by briefly boosting natural production