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UV exposure (and vitamin D itself) can have a healthy, regulatory effect on the microbiome of the skin as well as the gut, with UVB light having a beneficial impact on the diversity and abundance of the bacteria species of the gut microbiome, and UVB as well as UVA benefitting the skin microbiome

However, variability in responsiveness across subgroups highlights the need for personalized treatment approaches

Cummings DE, Clement K, Purnell JQ, Vaisse C, Foster KE, Frayo RS, et al

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4,26 Findings from certain studies suggest that GLP-1 has direct effects on the liver, adipose tissue and skeletal muscle and whether GLP-1R is expressed in these tissues is currently debated