semaglutide and hiv slows epigenetic aging in a randomized trial of HIV-associated lipohypertrophy Ozempic reduces severity of liver

Thyroid disorders become more common during midlife, and subclinical hypothyroidism can contribute to weight gain and metabolic dysfunction

Individuals should be advised to contact their GP or diabetes specialist nurse promptly if they experience: Persistent vomiting or diarrhoea lasting more than 24 hours Inability to maintain adequate fluid intake Signs of dehydration : dizziness, reduced urine output, dark-coloured urine, dry mouth, or excessive thirst Unexplained fatigue or weakness Swelling of the ankles, feet, or face (which may indicate fluid retention or worsening kidney function) Patients with pre-existing kidney disease should be particularly vigilant and may benefit from more frequent contact with their healthcare team during treatment initiation

Practical considerations for getting started If you and your healthcare provider decide that GLP-1 microdosing is worth exploring for your autoimmune condition, here are the practical details that matter

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Youll lose weight, but your body composition and metabolic rate suffer