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Optimize Long-Term Outcomes If lipedema is present, the goal isnt just short-term weight lossits: Symptom improvement Functional mobility improvement Sustainable health changes The Bottom Line GLP-1 medications like semaglutide and tirzepatide are showing early promise in lipedemanot just for weight loss, but for potentially improving the underlying biology of the condition

doi:10.1353/pbm.2015.0034

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In fact, changes have already begun to take shape, following the steady decline in alcohol consumption over the past decade