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GLP-1-induced AMPK and LXR-mediated ABCA1 expression are involved in GLP-1 protective effects (Figure 8)

This then reduces to a neutral ascorbate molecule [14]

The journey from the discovery of the GLP-1 hormone to the treatment of diabetes and then obesity has been a long and tortuous one, spanning more than four decades and involving hundreds of researchers from academia and the pharmaceutical industry

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