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These effects are central to the weight loss observed with GLP-1 receptor agonists and dual incretin agonists

The most common side effects are gastrointestinal nausea, constipation, or mild abdominal discomfort and are most pronounced during dose escalation

Most Common Side Effects of Zoloft Withdrawal Loss of appetite and Libido Nausea and Vomiting Dizziness Nervousness and Restlessness Stomach pain Drowsiness and Fatigue Headache Indigestion Sweating Tremors More Serious Side Effects of Zoloft Withdrawal Changes in appetite or weight New or worse anxiety or panic attacks Agitation, restlessness, anger, or irritability Manic episodes Difficulty sleeping An increase in activity or Craving more than the usual dose Suicide attempts Eye pain Seizures or convulsions Acting on dangerous impulses Aggressive or violent behavior Thoughts about suicide or dying New or worse depression Allergic reactions to Zoloft are rare, but prompt medical attention is necessary if they occur

In fact, continuing or starting an exercise routine while taking GLP-1s is one of the smartest ways to support long-term results

In LIVE, 241 clinically stable patients with HFrEF were randomized to receive liraglutide at 1.8 mg per day or placebo [28]