Chen D, Li Q, Liang H, Huang L, Zhou H, Zheng X, et al
remains investigational, not approved
most common side effects are mild injection-site reactions (temporary redness, itching) with subcutaneous administration
Patients with favorable genetic profiles may reach goal weight on lower doses (preserving medication cost and minimizing side effects), while those with less-responsive variants can switch to dual-compound protocols like GLP-Squared Injection ($289 monthly) earlier in treatment
Alloxan hepatic metabolism may have been responsible for the increase in ALT/AST levels in diabetic animals, since the structural similarity with the glucose molecule allows its absorption by the cell through the GLUT2 transporter 38 , occasioning possible damage to cells which express this carrier