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Despite its therapeutic potential, critics of the ketogenic diet (KD) raise concerns about the high intake of saturated fats and processed meats, which are traditionally associated with increased risks of cardiovascular disease, diabetes, and Alzheimer's disease (AD) (214)

In addition, TMP195 continuously activates MAPK and NF-B signaling pathway phosphorylation, suggesting that it promotes M1 polarization through the synergistic action of epigenetic modification and inflammatory signaling pathways (54)

Cycloheximide (CHX), tunicamycin (TUN), 6-diazo-5-oxo-L-norleucine (DON), reduced L-glutathione (GSH), reduced glutathione ethyl ester (GSHee) were from Sigma-Aldrich (St

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10.1007/BF00371781 Arch